Holistic Cancer Care Blog
Cancer Metabolism as a Therapeutic Target
Cancer Metabolism as a Therapeutic Target and Review of Interventions (MDPI; Multidisciplinary Digital Publishing Institute)
Main points: Therapies aimed at targeting cancer metabolism may prove to be more effective than traditional treatments. Despite increasing interest, the potential for cancer metabolism as a treatment approach is still largely underexplored.
Implications: Treatments targeting cancer metabolism could potentially be more effective than conventional therapies. Although there has been growing interest, cancer metabolism remains an underutilized approach in treatment strategies.
Abstract: Cancer is amenable to low-cost treatments, given that it has a significant metabolic component, which can be affected through diet and lifestyle change at minimal cost. The Warburg hypothesis states that cancer cells have an altered cell metabolism towards anaerobic glycolysis. Given this metabolic reprogramming in cancer cells, it is possible to target cancers metabolically by depriving them of glucose. In addition to dietary and lifestyle modifications which work on tumors metabolically, there are a panoply of nutritional supplements and repurposed drugs associated with cancer prevention and better treatment outcomes. These interventions and their evidentiary basis are covered in the latter half of this review to guide future cancer treatment.
Read the full research article:
Keywords: cancer metabolism; Warburg effect; glycolysis; ketogenic diet; repurposed drugs; lifestyle interventions
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By the Holistic GoCancerGo Team